HIV Mutation Detail Information

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Mutation Information

Mutation Site	M184V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M184V+rt.Q151M+rt.F116Y+rt.Y115F;rt.M184V+rt.F160M+rt.Q151M+rt.F116Y+rt.Y115F;rt.M184V+rt.Q182G+rt.F160M+rt.Q151M+rt.F116Y+rt.Y115F
Relevant Drug	entecavir (ETV);lamivudine (LAM);tenofovir alafenamide (TAF);islatravir (ISL);zidovudine (AZT)

Literature Information

PubMed PMID	32080249
Published Year	2020
Journal	Scientific reports
Title	Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.
Author	Yasutake Y,Hattori SI,Tamura N,Matsuda K,Kohgo S,Maeda K,Mitsuya H
Evidence	Additionally, we experimentally simulated previously reported ETV/3TC resistance for HBV using HIVY115F/F116Y/Q151M with F160M/M184V (L180M/M204V in HBV RT) substituted.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation