Mutation Information
Mutation Site
|
M184V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
A |
Relevant Drug
|
NRTIs |
Country
|
Uganda |
Literature Information
PubMed PMID
|
32005262
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
AIDS research and therapy |
Title
|
Comparison of HIV drug resistance profiles across HIV-1 subtypes A and D for patients receiving a tenofovir-based and zidovudine-based first line regimens in Uganda. |
Author
|
Ayitewala A,Kyeyune F,Ainembabazi P,Nabulime E,Kato CD,Nankya I |
Evidence
|
The most prevalent Nucleoside Reverse Transcriptase Inhibitor (NRTI) mutations were M184V/I (67.3%), K219/Q/E (22.6%) and K65R (21.1%). While K103N (50.8%) and G190A/S/E/G (29.1%) were the most prevalent Non-Nucleoside Reverse Transcriptase Inhibitor (NNTRI) mutations.
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