HIV Mutation Detail Information

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Mutation Information

Mutation Site	M184V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	emtricitabine (FTC)

Literature Information

PubMed PMID	31879782
Disease	HIV infection/AIDS
Published Year	2020
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Title	Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in a Rapid-Initiation Model of Care for Human Immunodeficiency Virus Type 1 Infection: Primary Analysis of the DIAMOND Study.
Author	Huhn GD,Crofoot G,Ramgopal M,Gathe J,Bolan R,Luo D,Simonson RB,Nettles RE,Benson C,Dunn K
Evidence	Two participants had emtricitabine RAMs (M184M/I and M184M/V) and 5 had a primary PI RAM, but none were darunavir RAMs. Five participants were found to have a transmitted INI mutation at position T97.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation