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Mutation Information
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Mutation Site
|
M184V |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
NRTIs |
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Country
|
Haiti |
Literature Information
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PubMed PMID
|
30640198
|
|
Disease
|
HIV infection/AIDS
|
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Published Year
|
2019 |
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Journal
|
The Pediatric infectious disease journal |
|
Title
|
High Levels of HIV-1 Drug Resistance in Children Who Acquired HIV Infection Through Mother to Child Transmission in the Era of Option B+, Haiti, 2013 to 2014. |
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Author
|
Louis FJ,Segaren N,Desinor O,Beard RS,Jean-Louis R,Chang J,Boisson S,Hulland EN,Wagar N,DeVos J,François K,Buteau J,Boncy J,Marston BJ,Domerçant JW,Yang C,Charles M |
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Evidence
|
The most frequent mutations were K103N/S (48.0%), M184V (37.5%), and G190A/S (15.1%), and Y181C/G/V (14.1%). Predicted drug resistance analysis revealed that 68.8% of the children had high-level resistance to NNRTIs and 11.5% had intermediate to high-level resistance to abacavir.
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HIV Mutation Detail Information