HIV Mutation Detail Information

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Mutation Information

Mutation Site	M184V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NRTIs

Literature Information

PubMed PMID	30352054
Disease	HIV infection/AIDS
Published Year	2018
Journal	PloS one
Title	Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial.
Author	Morales-Ramirez J,Bogner JR,Molina JM,Lombaard J,Dicker IB,Stock DA,DeGrosky M,Gartland M,Pene Dumitrescu T,Min S,Llamoso C,Joshi SR,Lataillade M
Evidence	In the GSK3532795 arms, 10/12 participants had emergent nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) mutations M184V, M184I/V, or M184I with consequent resistance to FTC.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation