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Mutation Information
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Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Finland |
Literature Information
|
PubMed PMID
|
28212411
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2017 |
|
Journal
|
PloS one |
|
Title
|
Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome. |
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Author
|
Abram ME,Ram RR,Margot NA,Barnes TL,White KL,Callebaut C,Miller MD |
|
Evidence
|
The 1 TN patient with emergent T97A in year 3 (from Study 236–0103) co-developed NRTI (M184V) resistance on EVG/COBI/FTC/TDF at their first protocol-defined virologic failure visit and then later regained virologic suppression by Week 144 at which point study drug was discontinued [89].
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HIV Mutation Detail Information