|
Mutation Information
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Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M184V+rt.K103N |
|
Relevant Drug
|
lamivudine (LAM);lopinavir(LPV);ritonavir;efavirenz (EFV) |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
21694608
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2011 |
|
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
|
Title
|
Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa. |
|
Author
|
Dlamini JN,Hu Z,Ledwaba J,Morris L,Maldarelli FM,Dewar RL,Highbarger HC,Somaroo H,Sangweni P,Follmann DA,Pau AK,Phidisa II Study Team. |
|
Evidence
|
NNRTI-DRM were found in 17/36 (47.2%) EFV-recipients, and M184V/I mutation in 14/40 (35.0%) 3TC-recipients.
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HIV Mutation Detail Information