|
Mutation Information
|
Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF);abacavir (ABC) |
|
Country
|
spain |
Literature Information
|
PubMed PMID
|
17559687
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2007 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Predictive factors of virological success to salvage regimens containing protease inhibitors in HIV-1 infected children. |
|
Author
|
Larru B,de Mendoza C,Bellón JM,de José MI,Mellado MJ,Soriano V,Muñoz-Fernandez MA,Ramos JT |
|
Evidence
|
M184V was found in 11 children (33%);3 of them (30.3%) were resistant to Abacavir and 1 of them (15.2%) was resistant to Tenofovir according to the virtual phenotype. At baseline, 42.4% of children have NNRTI mutations;30.3% have the K103N and 15.2% the Y181C.
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HIV Mutation Detail Information