Mutation Information
Mutation Site
|
M184I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Viral Reference
|
K03455
|
Relevant Drug
|
NRTIs |
Country
|
France |
Literature Information
PubMed PMID
|
33624081
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2021 |
Journal
|
The Journal of antimicrobial chemotherapy |
Title
|
Deep sequencing analysis of M184V/I mutation at the switch and at the time of virological failure of boosted protease inhibitor plus lamivudine or boosted protease inhibitor maintenance strategy (substudy of the ANRS-MOBIDIP trial). |
Author
|
Delaugerre C,Nere ML,Eymard-Duvernay S,Armero A,Ciaffi L,Koulla-Shiro S,Sawadogo A,Ngom Gueye NF,Ndour CT,Mpoudi Ngolle M,Amara A,Chaix ML,Reynes J,ANRS 12286/MOBIDIP study group. |
Evidence
|
M184I mutation was always associated with a STOP codon, suggesting defective virus.
|
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|