HIV Mutation Detail Information

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Mutation Information

Mutation Site	M184I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	Canada

Literature Information

PubMed PMID	33217873
Disease	HIV infection/AIDS
Published Year	2020
Journal	Medicine
Title	Impact of previous HIV resistance and virologic failures on virologic outcome following a switch to dolutegravir with 2 NRTIs among people living with HIV.
Author	Sangaré MN,Baril JG,de Pokomandy A,Laprise C,Deshaies C,Klein M,Thomas R,Tremblay C,Roger M,Pexos C,Greenwald Z,Machouf N,Durand M,Hardy I,Dakouo M,Laporte L,Trottier H
Evidence	The most common resistance mutation detected before switch (index date) was M184V/I and was documented in 11.3% (54/478) of PLHIV in the exposed group (one of whom experienced post-switch virologic failure) and in 5.1% (37/721) of non-exposed group (none of whom experienced post-switch virologic failure).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation