Mutation Information
Mutation Site
|
M184I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Literature Information
PubMed PMID
|
32759675
|
Published Year
|
2020 |
Journal
|
Viruses |
Title
|
Fact and Fiction about 1%: Next Generation Sequencing and the Detection of Minor Drug Resistant Variants in HIV-1 Populations with and without Unique Molecular Identifiers. |
Author
|
Zhou S,Swanstrom R |
Evidence
|
Using the raw sequence reads we detected "apparent" DRMs across the sequenced HIV RT region in the range of 0.1-1%, with the M184I mutation breaking through the 1% cut-off in the three replicates, which would have been reported as a minority DRM by other protocols.
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