Mutation Information
Mutation Site
|
M184I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Literature Information
PubMed PMID
|
32512519
|
Published Year
|
2020 |
Journal
|
EBioMedicine |
Title
|
Dolutegravir plus lamivudine for hiv treatment: Does the historical genotype really matter? |
Author
|
Giacomelli A,Conti F,Rusconi S |
Evidence
|
While this effect could be class- or drug-specific, M184V/I data suggest that the duration of virological suppression has a critical role in decreasing the amount of previously resistant variants below a clinically relevant threshold.
|
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