|
Mutation Information
|
Mutation Site
|
M184I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;CRF01_AE;CRF07_BC;CRF08_BC |
|
Relevant Drug
|
lamivudine (LAM);efavirenz (EFV);nevirapine (NPV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31922125
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
EClinicalMedicine |
|
Title
|
Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017). |
|
Author
|
Zuo L,Liu K,Liu H,Hu Y,Zhang Z,Qin J,Xu Q,Peng K,Jin X,Wang JH,Zhang C |
|
Evidence
|
Low percentages of NRTI and NNRTI mutations, but a very high percentage (47.7%) of PI mutation (M46I/L) occurred in CRF01_AE;in contrast, high percentages of NRTI (M184I/V) and NNRTI (K103N/S and Y181C/I) mutations were observed in subtype B.
|
|
|
HIV Mutation Detail Information