HIV Mutation Detail Information

> M184I Search Result


Mutation Information
Mutation Site M184I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype A
Viral Reference K03455.1
Relevant Drug NRTIs
Literature Information
PubMed PMID 31885806
Published Year 2019
Journal Oxidative medicine and cellular longevity
Title HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
Author Bayurova E,Jansons J,Skrastina D,Smirnova O,Mezale D,Kostyusheva A,Kostyushev D,Petkov S,Podschwadt P,Valuev-Elliston V,Sasinovich S,Korolev S,Warholm P,Latanova A,Starodubova E,Tukhvatulin A,Latyshev O,Selimov R,Metalnikov P,Komarov A,Ivanova O,Gorodnicheva T,Kochetkov S,Gottikh M,Strumfa I,Ivanov A,Gordeychuk I,Isaguliants M
Evidence The most frequent mutation of resistance to NRTI worldwide is M184V/I, followed by K65R/N, L74V/I, Y115F, and Q151M, and the most prevalent for FSU_A is M184V, followed by K65R/N.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation