|
Mutation Information
|
Mutation Site
|
M184I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
darunavir (DRV);cobicistat;emtricitabine (FTC);tenofovir alafenamide |
|
Country
|
Canada;America;Belgium;France;Germany;Italy;Poland;Russia;Spain;England |
Literature Information
|
PubMed PMID
|
29683855
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
AIDS (London, England) |
|
Title
|
A week-48 randomized phase-3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients. |
|
Author
|
Eron JJ,Orkin C,Gallant J,Molina JM,Negredo E,Antinori A,Mills A,Reynes J,Van Landuyt E,Lathouwers E,Hufkens V,Jezorwski J,Vanveggel S,Opsomer M,AMBER study group. |
|
Evidence
|
One patient (D/C/F/TAF) was identified with M184I/V conferring resistance to emtricitabine.
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HIV Mutation Detail Information