|
Mutation Information
|
Mutation Site
|
M184I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
25259833
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
AIDS (London, England) |
|
Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
|
Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
|
Evidence
|
M184V/I alone was the most common NRTI-resistance mutation pattern, occurring in 36% (79/218) of patients receiving just thymidine-alog containing regimens (ZDV and/or d4T and 3TC), 23% (14/61) receiving just nonthymidine-alog regimens (abacavir and/or ddI and 3TC), and 14% (12/87) receiving both thymidine-alog and nonthymidine-alog regimens.
|
|
|
HIV Mutation Detail Information