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Mutation Information
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Mutation Site
|
M184I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
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Viral Reference
|
K03455.1
|
Literature Information
|
PubMed PMID
|
16524459
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2006 |
|
Journal
|
BMC infectious diseases |
|
Title
|
DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes. |
|
Author
|
Garriga C,Menéndez-Arias L |
|
Evidence
|
The rules used by other algorithms (i.e. Retrogram, ANRS or RegaInst) do not take into account the effects of antagonistic mutations, or make a limited used of them (i.e. HIVDB assumes only the suppressive effects of K65R, L74V, L100I, Y181C and M184I/V on AZT resistance, and M184V on tenofovir resistance mediated by K65R).
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HIV Mutation Detail Information