HIV Mutation Detail Information

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Mutation Information
Mutation Site M168I
Mutation Type Amino acid level
Gene/Protein/Region Type Nef
Country Netherlands
Literature Information
PubMed PMID 33800773
Disease HIV infection/AIDS
Published Year 2021
Journal Viruses
Title Nef Obtained from Individuals with HIV-1 Vary in Their Ability to Antagonize SERINC3- and SERINC5-Mediated HIV-1 Restriction.
Author Kruize Z,van Nuenen AC,van Wijk SW,Girigorie AF,van Dort KA,Booiman T,Kootstra NA
Evidence Previous reports indicated that some naturally occurring mutations in Nef could affect both SERINC3 and SERINC5 (N51T, H116N, V148L/X, 161N and M168I/X), while others only affected SERINC3 (8R, 9S, 11P, 12G, 14A, 15A, 21K, 28E, 43I, 182E and 188S) or SERINC5 (14S, 21R, 54D, 63E, 81F, 120F, 157N and 158K).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation