|
Mutation Information
|
Mutation Site
|
M133T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
|
Viral Reference
|
GQ477480;
GQ331048;
DQ298165;
AF043580;
AF297621;
DQ315786;
AB246317;
AY934774 |
|
Country
|
Philippines |
Literature Information
|
PubMed PMID
|
24009186
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2014 |
|
Journal
|
Journal of medical virology |
|
Title
|
Unique surface gene variants of hepatitis B virus isolated from patients in the Philippines. |
|
Author
|
Baclig MO,Alvarez MR,Gopez-Cervantes J,Natividad FF |
|
Evidence
|
The amino acid substitution M133T which was associated with failure of HBsAg detection was found in one isolate (7%, 1/15), while the amino acid substitution D144A which was associated with vaccine escape was observed in one isolate (7%, 1/15).
|
|
|
HBV Mutation Detail Information