HBV Mutation Detail Information

> M133T Search Result

Mutation Information

Mutation Site	M133T
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Combined Mutation	s.M133T+s.I110M;s.R169P+s.M133T+s.I110M

Literature Information

PubMed PMID	16461214
Published Year	2005
Journal	Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title	Mechanism of HBV genome variability and replication of HBV mutants.
Author	Tong S
Evidence	Several core promoter mutants were defective in virion secretion, and mapping experiments revealed three missense mutations in the small envelope protein to be responsible: I110M, G119E, and R169P The effect of I110M and G119E mutations can be relieved by another point mutation that creates a novel N-linked glycosylation site.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation