|
Mutation Information
|
Mutation Site
|
M133I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
22442974
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Zhurnal mikrobiologii, epidemiologii i immunobiologii |
|
Title
|
[Heterogeneity of hepatitis B virus and diagnostic potential of modern test systems for the detection of HBsAg]. |
|
Author
|
Kuzin SN,Zabotina EE,Zabelin NN,Kudriavtseva EN,Samokhvalov EI,Borisova OV,Manina TA,Lisitsina EV,Kuzina LE,Malyshev NA,Lavrov VF |
|
Evidence
|
Amino acid substitutions G145A, M133I, S132T localized in the main hydrophilic region and P217L, S207N, V184A localized in the C-end of the protein C that are connected with diagnostic and vaccine escape were identified in 5 isolates.
|
|
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HBV Mutation Detail Information