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Mutation Information
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Mutation Site
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L90M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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PR |
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Combined Mutation
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pr.L90M+pr.I84V |
Literature Information
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PubMed PMID
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33503916
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Published Year
|
2021 |
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Journal
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Molecules (Basel, Switzerland) |
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Title
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Structural Impacts of Drug-Resistance Mutations Appearing in HIV-2 Protease. |
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Author
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Laville P,Petitjean M,Regad L |
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Evidence
|
For example, the D30N mutant induced 5 MCS atoms with one exhibiting large shift of 2.9 A, while the L90M mutant caused four small shifts at residues 90_A/B and 97_B with a magnitude varying from 0.35 to 0.48 A (Figure 3B and Figure A3).
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HIV Mutation Detail Information