Mutation Information
Mutation Site
|
L90M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
33085662
|
Published Year
|
2020 |
Journal
|
PLoS genetics |
Title
|
Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease. |
Author
|
Zhang TH,Dai L,Barton JP,Du Y,Tan Y,Pang W,Chakraborty AK,Lloyd-Smith JO,Sun R |
Evidence
|
The distribution of epistasis ranged from -0.69 (M46I and L90M) to 2.34 (L76V and V82F) and 86.6% of pairwise interactions between RAMs are positive.
|
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