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Mutation Information
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Mutation Site
|
L90M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
|
PubMed PMID
|
32053707
|
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Published Year
|
2020 |
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Journal
|
PLoS pathogens |
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Title
|
HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle. |
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Author
|
Jurczyszak D,Zhang W,Terry SN,Kehrer T,Bermúdez González MC,McGregor E,Mulder LCF,Eckwahl MJ,Pan T,Simon V |
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Evidence
|
Briefly, HIV-MDR1 encodes two major protease inhibitor resistance associated mutations (PR I84V and L90M) while HIV-MDR2 only has one (PR L90M).
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HIV Mutation Detail Information