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Mutation Information
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Mutation Site
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L90M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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PR |
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Relevant Drug
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PIs |
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Country
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Namibia |
Literature Information
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PubMed PMID
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30568984
|
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Disease
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HIV infection/AIDS
|
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Published Year
|
2018 |
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Journal
|
Open forum infectious diseases |
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Title
|
Human Immunodeficiency Virus-1 Drug Resistance Patterns Among Adult Patients Failing Second-Line Protease Inhibitor-Containing Regimens in Namibia, 2010-2015. |
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Author
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Sawadogo S,Shiningavamwe A,Roscoe C,Baughman AL,Negussie T,Mutandi G,Yang C,Hamunime N,Agolory S |
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Evidence
|
The prevalence of the most common mutations observed for NRTIs were as follows: any 138 (37.7%); M184V 114 (31.1%); T215Y/F 46 (12.6%);D67N 36 (9.8%);M41L 32 (8.7%); K219Q/E 31 (8.5%);K70R 26 (7.1%);and L210W 15 (4.1%). For protease inhibitors (PIs), the most common mutations observed were as follows: any 37 (10.1%);V82A 25 (6.8%); M46I/L 24 (6.6%); L76V 12 (3.3%); I54V 10 (2.7%); L90M 7 (1.9%);and I84V 6 (1.6%).
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HIV Mutation Detail Information