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Mutation Information
Mutation Site L90M
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Relevant Drug PIs
Literature Information
PubMed PMID 28645089
Published Year 2017
Journal Journal of molecular graphics & modelling
Title Drug Resistance Mechanism of L10F, L10F/N88S and L90M mutations in CRF01_AE HIV-1 protease: Molecular dynamics simulations and binding free energy calculations.
Author Vasavi CS,Tamizhselvi R,Munusami P
Evidence In this work, we examined the effect of non active site mutations L10F, L10F/N88S and L90M with nelfinavir using molecular dynamics simulation and binding free energy calculations.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation