HIV Mutation Detail Information

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Mutation Information

Mutation Site	L90M
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs

Literature Information

PubMed PMID	28645089
Published Year	2017
Journal	Journal of molecular graphics & modelling
Title	Drug Resistance Mechanism of L10F, L10F/N88S and L90M mutations in CRF01_AE HIV-1 protease: Molecular dynamics simulations and binding free energy calculations.
Author	Vasavi CS,Tamizhselvi R,Munusami P
Evidence	In this work, we examined the effect of non active site mutations L10F, L10F/N88S and L90M with nelfinavir using molecular dynamics simulation and binding free energy calculations.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation