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Mutation Information
|
Mutation Site
|
L83V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Amino acid_Mutation
|
G350T |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
French Guiana |
Literature Information
|
PubMed PMID
|
33238632
|
|
Disease
|
High grade squamous intraepithelial lesion;
Low grade squamous intraepithelial lesion
|
|
Published Year
|
2020 |
|
Journal
|
Microorganisms |
|
Title
|
E6/E7 Sequence Diversity of High-Risk Human Papillomaviruses in Two Geographically Isolated Populations of French Guiana. |
|
Author
|
Nacher M,Godefroy G,Dufit V,Douine M,Najioullah F,Césaire R,Thomas N,Drak Alsibai K,Adenis A,Lacoste V |
|
Evidence
|
They showed 98.3%-100% nucleotide identity and 97.6%-100% amino acid identity with the representative sequences of the different HPV16 lineages and sublineages. Based on E6 protein sequences, the 18 isolates grouped into four distinct variants corresponding to the reference sequence as well as to variants L83V, R10T/Q14D/H78Y, and R10I/Q14D/H78Y (Supplementary Table S3).
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HPV Mutation Detail Information