|
Mutation Information
|
Mutation Site
|
L83V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Amino acid_Mutation
|
T350G |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
31708575
|
|
Published Year
|
2020 |
|
Journal
|
British journal of cancer |
|
Title
|
Human papillomavirus as a driver of head and neck cancers. |
|
Author
|
Sabatini ME,Chiocca S |
|
Evidence
|
This variant leads to an amino acid change at residue 83 from a leucine to a valine (denoted L83V) and may increase the pathogenicity of HPV16 by enhancing persistency of infection in cervical cancer, although the results are still controversial.
|
|
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HPV Mutation Detail Information