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Mutation Information
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Mutation Site
|
L83V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Amino acid_Mutation
|
T350G |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
Mexico |
Literature Information
|
PubMed PMID
|
31552532
|
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
|
Published Year
|
2019 |
|
Journal
|
Archives of virology |
|
Title
|
Mutational landscape and intra-host diversity of human papillomavirus type 16 long control region and E6 variants in cervical samples. |
|
Author
|
Escobar-Escamilla N,González-Martínez BE,Araiza-Rodríguez A,Fragoso-Fonseca DE,Pedroza-Torres A,Landa-Flores MG,Garcés-Ayala F,Mendieta-Condado E,Díaz-Quiñonez JA,Castro-Escarpulli G,Ramírez-González JE |
|
Evidence
|
Moreover, the most frequent mutations, both in samples from this study and in the available sequences from Mexican isolates in the GenBank database were LCR-G7518A, which is involved in carcinogenesis, and E6-T350G (producing L83V), associated with persistence of infection.
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HPV Mutation Detail Information