HPV Mutation Detail Information

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Mutation Information

Mutation Site	L83V
Mutation Type	Amino acid level
Gene/Protein/Region Type	E6
Genotype/Subtype	HPV16
Viral Reference	AF125673.1

Literature Information

PubMed PMID	27806689
Published Year	2016
Journal	BMC genomics
Title	Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology.
Author	Jackson R,Rosa BA,Lameiras S,Cuninghame S,Bernard J,Floriano WB,Lambert PF,Nicolas A,Zehbe I
Evidence	A previous study of HPV16 integration propensity with respect to the variants did not demonstrate a statistically significant difference (P-value = 0.28, two-tailed Fisher's exact test) between EPE6 (3 episomal and 20 integrated cases) and the E-T350G variant (6 episomal and 16 integrated cases, responsible for one of the residue changes also found in AAE6: L83V).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation