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Mutation Information
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Mutation Site
|
L83V |
|
Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
E6 |
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Genotype/Subtype
|
HPV16 |
|
Country
|
Sweden |
Literature Information
|
PubMed PMID
|
16519914
|
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Published Year
|
2006 |
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Journal
|
Virology |
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Title
|
HPV16 E6 natural variants exhibit different activities in functional assays relevant to the carcinogenic potential of E6. |
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Author
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Lichtig H,Algrisi M,Botzer LE,Abadi T,Verbitzky Y,Jackman A,Tommasino M,Zehbe I,Sherman L |
|
Evidence
|
On the other hand, L83V displayed more efficient degradation of Bax and binding to E6BP, but lower binding to hDlg.
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HPV Mutation Detail Information