HPV Mutation Detail Information

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Mutation Information

Mutation Site	L83V
Mutation Type	Amino acid level
Gene/Protein/Region Type	E6
Genotype/Subtype	HPV16

Literature Information

PubMed PMID	12050680
Disease	Squamous-cell carcinoma; Head and neck carcinoma
Published Year	2002
Journal	Magyar onkologia
Title	[Causal association between human papilloma virus infection and head and neck and esophageal squamous cell carcinoma].
Author	Szentirmay Z,Szántó I,Bálint I,Pólus K,Remenár E,Tamás L,Szentkúti G,Melegh Z,Nagy P,Kásler M
Evidence	DNA was extracted from 150 fresh or paraffin embedded biopsy specimens, and analyzed for HPV by PCR with 15 sets of consensus primers directed to conserved regions of L1 gene, three sets of HPV16E6 primers (specific for the HPV 16 prototype and L83V variant), and sets of primers specific for the E6 gene of other mucosa type HPVs including HPV 6, 11, 16, 18, 52, 58, 66 and 73.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation