Mutation Information
Mutation Site
|
L76V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Relevant Drug
|
PIs |
Literature Information
PubMed PMID
|
32411655
|
Published Year
|
2020 |
Journal
|
Frontiers in chemistry |
Title
|
An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site Dissimilarities. |
Author
|
Alves NG,Mata AI,Luís JP,Brito RMM,Simões CJV |
Evidence
|
Major mutations: D30N, V32I, L33F, M46IL, I47VA, G48VM, I50VL, I54VTALM, L76V, V82AFTSL, I84V, N88SD, and L90M;Minor mutations: L10FIVRY, V11IL, K20RIMTV, L23I, L24IFM, M36I, K43T, M46V, G48ASTQL, F53LY, I54ST, Q58E, A71VTIL, G73STCADV, T74PS, V82MC, N83DS, I84AC, I85V, N88TG, and L89VT.
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