Mutation Information
Mutation Site
|
L76V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Relevant Drug
|
PIs |
Country
|
Namibia |
Literature Information
PubMed PMID
|
30568984
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2018 |
Journal
|
Open forum infectious diseases |
Title
|
Human Immunodeficiency Virus-1 Drug Resistance Patterns Among Adult Patients Failing Second-Line Protease Inhibitor-Containing Regimens in Namibia, 2010-2015. |
Author
|
Sawadogo S,Shiningavamwe A,Roscoe C,Baughman AL,Negussie T,Mutandi G,Yang C,Hamunime N,Agolory S |
Evidence
|
For protease inhibitors (PIs), the most common mutations observed were as follows: any 37 (10.1%);V82A 25 (6.8%); M46I/L 24 (6.6%); L76V 12 (3.3%); I54V 10 (2.7%); L90M 7 (1.9%);and I84V 6 (1.6%).
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