HIV Mutation Detail Information

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Mutation Information
Mutation Site L76V
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Relevant Drug abacavir (ABC);stavudine (D4T);didanosine (DDI);emtricitabine (FTC);emtricitabine (FTC);lamivudine (LAM);tenofovir (TDF);efavirenz (EFV);etravirine(ETR);nevirapine (NPV);rilpivirine (RPV);atazanavir (ATV);darunavir (DRV);fosamprenavir (FPV);indinavir (IDV);lopinavir (LPV);nelfinavir (NFV);saquinavir (SQV);tipranavir (TPV)
Country India
Literature Information
PubMed PMID 30315192
Disease HIV infection/AIDS
Published Year 2018
Journal Scientific reports
Title Antiretroviral resistance, genotypic characterization and origin of Human Immunodeficiency Virus among the infected wives of Intravenous drug users in Manipur.
Author Sharma AL,Singh TR,Singh LS
Evidence One sample, Manipur017 harbored multiple mutations in NRTIs (K65R, M184V), NNRTIs (Y188L) and PIs (I54V, L76V and I84V) which conferred high-level resistance to abacavir (ABC), didanosine (DDI), emtricitabine (FTC), lamivudine (3TC), and intermediate-level resistance to stavudine (d4T), tenofovir (TDF), high or intermediate level resistance to all NNRTIs and PIs (Table 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation