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HIV Mutation Detail Information

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Mutation Information
Mutation Site L765H
Mutation Type Amino acid level
Gene/Protein/Region Type Gp41
Literature Information
PubMed PMID 21569545
Published Year 2011
Journal Retrovirology
Title Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity.
Author Bhakta SJ,Shang L,Prince JL,Claiborne DT,Hunter E
Evidence The subsequent addition of L771S/LLLI774SHSN to mutant A results in mutant B, the addition of LL784HQ to mutant B results in mutant C, the additional changes of Y795S/LL799HQ/Y802S to mutant C produce mutant D, and LL814AA/LL855AA was combined with mutant D to create mutant E.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation