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Mutation Information
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Mutation Site
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L74V |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
NRTIs |
|
Country
|
USA |
Literature Information
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PubMed PMID
|
31443633
|
|
Disease
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HIV infection/AIDS
|
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Published Year
|
2019 |
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Journal
|
BMC infectious diseases |
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Title
|
Trend of HIV transmitted drug resistance before and after implementation of HAART regimen restriction in the treatment of HIV-1 infected patients in southern Taiwan. |
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Author
|
Weng YW,Chen IT,Tsai HC,Wu KS,Tseng YT,Sy CL,Chen JK,Lee SS,Chen YS |
|
Evidence
|
The NRTI mutations included K65R (0.27%), D67N (0.27%), L74 V (0.27%), M184 V (1.06%), L210 W (0.2%) and T215S (0.53%). For NNRTIs, the most prevalent drug resistance mutations were K103 N (1.59%), V179D + K103R (1.33%), Y181C (0.80%), V108I (0.53%), Y188L (0.53%), G190A (0.53%), H221Y (0.53%), Y318F (0.53%), A98G (0.27%), V106A (0.27%), E138A (0.27%), E138R (0.27%), Y188C (0.27%) and M230 L (0.27%).
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HIV Mutation Detail Information