|
Mutation Information
|
Mutation Site
|
L74V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
29861843
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Oncotarget |
|
Title
|
HIV-1 integrase strand-transfer inhibitor resistance in southern Taiwan. |
|
Author
|
Tsai HC,Chen IT,Wu KS,Tseng YT,Sy CL,Chen JK,Lee SS,Chen YS |
|
Evidence
|
None of the 184 patients had TDR to INSTIs. However, 16 patients harboured virus with INSTI polymorphisms or substitution mutations, including L74I (4.9%), L74V (2.2%), T66 S (0.5%), V151I (0.5%), and L68V (0.5%)
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HIV Mutation Detail Information