HIV Mutation Detail Information

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Mutation Information

Mutation Site	L74V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	B
Relevant Drug	NRTIs

Literature Information

PubMed PMID	17500586
Disease	HIV infection/AIDS
Published Year	2007
Journal	PLoS computational biology
Title	HIV-1 subtype B protease and reverse transcriptase amino acid covariation.
Author	Rhee SY,Liu TF,Holmes SP,Shafer RW
Evidence	Different patterns of covariation were frequently observed for different mutations at the same position including the RT mutations T69D versus T69N, L74V versus L74I, V75I versus V75M, T215F versus T215Y, and K219Q/E versus K219N/R, and the protease mutations M46I versus M46L, I54V versus I54M/L, and N88D versus N88S.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation