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Mutation Information
|
Mutation Site
|
L74M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
dolutegravir (DTG);lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
33196554
|
|
Published Year
|
2021 |
|
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
|
Title
|
Simulating HIV Breakthrough and Resistance Development During Variable Adherence to Antiretroviral Treatment. |
|
Author
|
Mulato A,Acosta R,Chang S,Martin R,Yant SR,Cihlar T,White K |
|
Evidence
|
MT-2 cells were infected with wild-type or low frequency M184V HIV-1, exposed to drug combinations, monitored for VB, and rebound virus was deep sequenced.
|
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HIV Mutation Detail Information