|
Mutation Information
|
Mutation Site
|
L74M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Genotype/Subtype
|
CRF02_AG |
|
Relevant Drug
|
INSTIs |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
32954411
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon. |
|
Author
|
Wenk BM,Mbunkah HA,Nsanwe NN,Mbu ET,Besong LM,Sama BA,Orock E,Leemann C,Metzner KJ |
|
Evidence
|
Overall, we detected 156 accessory INSTI DRMs in 140 (140/255, 54.9%) ART-naive individuals, with the most common ones being L74I (78/255, 30.6%), E157Q (34/255, 13.3%), T97A (22/255, 8.6%) and L74M (12/255, 4.7%) (Table 2 and Table S3).
|
|
|
HIV Mutation Detail Information