HIV Mutation Detail Information

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Mutation Information

Mutation Site	L74M
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Genotype/Subtype	C
Country	India

Literature Information

PubMed PMID	28149058
Disease	HIV infection/AIDS
Published Year	2016
Journal	Bioinformation
Title	Effect of HIV-1 Subtype C integrase mutations implied using molecular modeling and docking data.
Author	Sachithanandham J,Konda Reddy K,Solomon K,David S,Kumar Singh S,Vadhini Ramalingam V,Alexander Pulimood S,Cherian Abraham O,Rupali P,Sridharan G,Kannangai R
Evidence	The molecular docking scores obtained for various mutation models like 3 individual accessory mutations (L74M, T97A and G163R), major mutation (Q148H, N155H) and also in combination of accessory (L74M, T97A and G163R), accessory and major mutations (L74M, T97A, G163R and Q148H), (L74M, T97A, G163R and N155H) were compared with wild type strain.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation