|
Mutation Information
|
Mutation Site
|
L74L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
INSTIs |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
32752001
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs. |
|
Author
|
Kirichenko A,Lapovok I,Baryshev P,van de Vijver DAMC,van Kampen JJA,Boucher CAB,Paraskevis D,Kireev D |
|
Evidence
|
Sub-subtype A6 and other genetic variants of subtype A included L74L in 3.7% and 86.4% of cases, L74I in 94.9% and 9.6%, L74M in 1.2% and 3%, and L74V in 0.1% and 1%, respectively.
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HIV Mutation Detail Information