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Mutation Information
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Mutation Site
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L74L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
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Genotype/Subtype
|
CRF01_AE |
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Relevant Drug
|
PIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31914782
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
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Journal
|
AIDS research and human retroviruses |
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Title
|
Prevalence of HIV-1 Drug-Resistance Genotypes Among Unique Recombinant Forms from Yunnan Province, China in 2016-2017. |
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Author
|
Deng X,Liu J,Li J,Yang B,Shu Y,Zhang M,Dong X |
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Evidence
|
A total of four mutation sites, including Y115F, L74LI, M41L, and E35D/G, were only detected in the URFs containing CRF01_AE, while the remaining mutation sites were detected in the URFs based on the RF B/C. Among them, A62A/V, T69D/N/T, H221H/Y, V90I, K238K/N, A71T/V, L10V/I, V11I, and Q58Q/E were only detected in the RF (B/C) (Fig. 4).
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HIV Mutation Detail Information