|
Mutation Information
|
Mutation Site
|
L74I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Genotype/Subtype
|
CRF02_AG |
|
Relevant Drug
|
INSTIs |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
32954411
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon. |
|
Author
|
Wenk BM,Mbunkah HA,Nsanwe NN,Mbu ET,Besong LM,Sama BA,Orock E,Leemann C,Metzner KJ |
|
Evidence
|
The distribution of accessory INSTI DRMs by HIV-1 subtype showed that the most prevalent polymorphisms L74I/M, E157Q and T97A are preferentially observed in individuals infected with HIV-1 subtype CRF02_AG (Table S4).
|
|
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HIV Mutation Detail Information