|
Mutation Information
|
Mutation Site
|
L74I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
NRTIs |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
32772079
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Impact of pretreatment low-abundance HIV-1 drug-resistant variants on virological failure among HIV-1/TB-co-infected individuals. |
|
Author
|
Chimukangara B,Giandhari J,Lessells R,Yende-Zuma N,Sartorius B,Samuel R,Khanyile KS,Stray-Pedersen B,Moodley P,Metzner KJ,Padayatchi N,Naidoo K,De Oliveira T |
|
Evidence
|
The LA-DRVs selected for were K65R, L74I and V106AI mutations.
|
|
|
HIV Mutation Detail Information