HIV Mutation Detail Information

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Mutation Information

Mutation Site	L74I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM);emtricitabine (FTC);tenofovir (TDF)
Country	Asia;Sub-saharan Africa;Europe;North America

Literature Information

PubMed PMID	31774913
Disease	HIV infection/AIDS
Published Year	2020
Journal	The Journal of infectious diseases
Title	Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I.
Author	Gregson J,Rhee SY,Datir R,Pillay D,Perno CF,Derache A,Shafer RS,Gupta RK
Evidence	Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation