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HIV Mutation Detail Information

> L74I Search Result


Mutation Information
Mutation Site L74I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NRTIs
Literature Information
PubMed PMID 30174310
Published Year 2018
Journal Cell chemical biology
Title The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase.
Author Takamatsu Y,Das D,Kohgo S,Hayashi H,Delino NS,Sarafianos SG,Mitsuya H,Maeda K
Evidence We previously selected an HIV-1EFdAR variant harboring M41L, D67Delta, T69G, K70R, L74I, V75T, M184V, T215F, and K219Q mutations (Figure 2A).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation