HIV Mutation Detail Information

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Mutation Information
Mutation Site L69A
Mutation Type Amino acid level
Gene/Protein/Region Type Vpr
Literature Information
PubMed PMID 32753492
Published Year 2020
Journal mBio
Title HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair.
Author Li D,Lopez A,Sandoval C,Nichols Doyle R,Fregoso OI
Evidence However, HIV-1 L64A/HIV-2 L69A was still able to recruit the DCAF1 adaptor protein, though at a slightly lower level than wild-type Vpr (Fig. 7A).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation