|
Mutation Information
|
Mutation Site
|
L67R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
12239337
|
|
Published Year
|
2002 |
|
Journal
|
Journal of virology |
|
Title
|
Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells. |
|
Author
|
Helt AM,Funk JO,Galloway DA |
|
Evidence
|
A C-terminal mutation, L67R, prevented induction of cdc25a.
|
|
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HPV Mutation Detail Information